For your listening pleasure. Hopefully.
10.30.2008
10.27.2008
Fart it up!
The Stink in Farts Controls Blood Pressure
livescience.com – Thu Oct 23, 3:21 pm ETA smelly rotten-egg gas in farts controls blood pressure in mice, a new study finds.
The unpleasant aroma of the gas, called hydrogen sulfide (H2S), can be a little too familiar, as it is expelled by bacteria living in the human colon and eventually makes its way, well, out.
The new research found that cells lining mice's blood vessels naturally make the gas and this action can help keep the rodents' blood pressure low by relaxing the blood vessels to prevent hypertension (high blood pressure). This gas is "no doubt" produced in cells lining human blood vessels too, the researchers said.
"Now that we know hydrogen sulfide's role in regulating blood pressure, it may be possible to design drug therapies that enhance its formation as an alternative to the current methods of treatment for hypertension," said Johns Hopkins neuroscientist Solomon H. Snyder, M.D., a co-author of the study detailed in the Oct. 24th issue of the journal Science.
Snyder and his colleagues compared normal mice to mice that were missing a gene for an enzyme known as CSE, long suspected as being responsible for making hydrogen sulfide. As they measured hydrogen sulfide levels taken from tissues of the CSE-deficient mice, the scientists found that the gas was depleted in the cardiovascular systems of the altered mice. By contrast, normal mice had higher levels of the gas, thereby showing that hydrogen sulfide is naturally made by mammalian tissues using CSE.
Next, the mice were subjected to higher blood pressures comparable to serious hypertension in humans. Scientists had them respond to a chemical called methacholine that relaxes normal blood vessels. The blood vessels of the CSE-lacking mice hardly relaxed, indicating that hydrogen sulfide is a huge contender for regulating blood pressure.
Hydrogen sulfide is the most recently discovered member of a family of gasotransmitters, small molecules inside our bodies with important physiological functions.
This study is the first to reveal that the CSE enzyme that triggers hydrogen sulfide is activated itself in the same way as other enzymes when they trigger their respective gasotransmitter, such as a nitric oxide-forming enzyme that also regulates blood pressure, Dr. Snyder said.
Because gasotransmitters are common in mammals all over the evolutionary tree, these findings on the importance of hydrogen sulfide are thought to have broad applications to human diseases, such as diabetes and neurodegenerative diseases.
The research was supported by grants from the U.S. Public Health Service and the Canadian Institutes of Health Research as well as a Research Scientist Award.
livescience.com – Thu Oct 23, 3:21 pm ETA smelly rotten-egg gas in farts controls blood pressure in mice, a new study finds.
The unpleasant aroma of the gas, called hydrogen sulfide (H2S), can be a little too familiar, as it is expelled by bacteria living in the human colon and eventually makes its way, well, out.
The new research found that cells lining mice's blood vessels naturally make the gas and this action can help keep the rodents' blood pressure low by relaxing the blood vessels to prevent hypertension (high blood pressure). This gas is "no doubt" produced in cells lining human blood vessels too, the researchers said.
"Now that we know hydrogen sulfide's role in regulating blood pressure, it may be possible to design drug therapies that enhance its formation as an alternative to the current methods of treatment for hypertension," said Johns Hopkins neuroscientist Solomon H. Snyder, M.D., a co-author of the study detailed in the Oct. 24th issue of the journal Science.
Snyder and his colleagues compared normal mice to mice that were missing a gene for an enzyme known as CSE, long suspected as being responsible for making hydrogen sulfide. As they measured hydrogen sulfide levels taken from tissues of the CSE-deficient mice, the scientists found that the gas was depleted in the cardiovascular systems of the altered mice. By contrast, normal mice had higher levels of the gas, thereby showing that hydrogen sulfide is naturally made by mammalian tissues using CSE.
Next, the mice were subjected to higher blood pressures comparable to serious hypertension in humans. Scientists had them respond to a chemical called methacholine that relaxes normal blood vessels. The blood vessels of the CSE-lacking mice hardly relaxed, indicating that hydrogen sulfide is a huge contender for regulating blood pressure.
Hydrogen sulfide is the most recently discovered member of a family of gasotransmitters, small molecules inside our bodies with important physiological functions.
This study is the first to reveal that the CSE enzyme that triggers hydrogen sulfide is activated itself in the same way as other enzymes when they trigger their respective gasotransmitter, such as a nitric oxide-forming enzyme that also regulates blood pressure, Dr. Snyder said.
Because gasotransmitters are common in mammals all over the evolutionary tree, these findings on the importance of hydrogen sulfide are thought to have broad applications to human diseases, such as diabetes and neurodegenerative diseases.
The research was supported by grants from the U.S. Public Health Service and the Canadian Institutes of Health Research as well as a Research Scientist Award.
10.24.2008
Ozarks here we come!!
Let us not focus on what could go wrong:
But instead, let us eagerly anticipate all that could go so very very right:
But instead, let us eagerly anticipate all that could go so very very right:
10.22.2008
10.20.2008
10.16.2008
In case you were wondering what to get me for Christmas...
1GB Clamshell Cell Phone Watch with Bluetooth
With its clamshell design and the rotary dial phone inspired keypad, this cell phone watch sure stands out from the previous models we have seen here at GeekAlerts.
With a compact clamshell style body and an outer display showing the current time and phone status, this cellphone works like a mega-modern digital watch. Next, you flip up the top to see a nice color OLED display and fully illuminated numeric keypad. When you are done admiring its design, you can start using the watch to start making phone calls or playing digital media files.
Using a compact cellphone has never been so easy. Simply use the included single piece bluetooth earphone, wired audio earphones with built-in MIC, or talk and listen directly from the phone itself.
The phone has speed dial, phonebook, and secure caller options to keep you in contact with only those people you want to talk to. In addition, you can use the phones software tools to set alarms, keep organized, do quick calculations, play MP3/MP4 files, and other functions to allow you the best use of your valuable time.
Features:
Main function: Watch or Necklace cellphone and multimedia player
Additional functions: Digital video and audio recorder, organizer, multi function calculator, alarm clock
Unlocked phone; can be used with any carrier and SIM card
Pre-loaded software tools include; Stopwatch, Calendar, Alarm, World Clock, Calculator, Currency Converter, Melody Composer, Video Games
Full bluetooth support; contains profiles for NINE bluetooth mobile phone services
Powerful built-in MIC and speaker; hear your phone ringtones and sound effects clearly
GSM Compatibility: Dual Band 900MHz, 1800MHz
GPRS Support: YES
Screen: 1.3 inch OLED, 128×160 with 260K colors
Memory: 1GB internal TF/microSD card
SIM Card Slot: YES - 1
Bluetooth Profiles: Handsfree, Headset, A2DP, AVRCP, SPP, DUN, OPP, FTP, BPP, HID - All Supported
Mobile Internet: WAP, Email - (if supported by your network provider)
Messages: SMS, MMS, EMS, Voice Mail Server, Broadcast Message (from provider)
1.3 Megapixel Still Camera, Resolution: 640×480, 320×240, 160×120, 128×128
Video Camera, Resolution: 128×128 - MPEG4 or H.263
Video Formats: MPEG, 3GP - Picture Formats: JPEG, BMP, GIF - Music and Sound Formats: MP3, MIDI, WAV, AMR, AWB
Battery Life: Talk Time: Up to 1.5 hrs, Music Play: Up to 4 hrs, Stand By: Up to 150 hrs
System: Windows 98SE / ME / 2000 / XP / Vista, MAC OS 9.2.2 or above
Languages: English, Spanish, Danish, Portuguese, Italian, German, Arabic, Chinese
Dimension: Face - 60mm x 19mm; Strap Max Length - 240mm
The 1GB Clamshell Cell Phone Watch with Bluetooth is available from the Chinavision website for 104.97 Euros (about $142 USD).
With its clamshell design and the rotary dial phone inspired keypad, this cell phone watch sure stands out from the previous models we have seen here at GeekAlerts.
With a compact clamshell style body and an outer display showing the current time and phone status, this cellphone works like a mega-modern digital watch. Next, you flip up the top to see a nice color OLED display and fully illuminated numeric keypad. When you are done admiring its design, you can start using the watch to start making phone calls or playing digital media files.
Using a compact cellphone has never been so easy. Simply use the included single piece bluetooth earphone, wired audio earphones with built-in MIC, or talk and listen directly from the phone itself.
The phone has speed dial, phonebook, and secure caller options to keep you in contact with only those people you want to talk to. In addition, you can use the phones software tools to set alarms, keep organized, do quick calculations, play MP3/MP4 files, and other functions to allow you the best use of your valuable time.
Features:
Main function: Watch or Necklace cellphone and multimedia player
Additional functions: Digital video and audio recorder, organizer, multi function calculator, alarm clock
Unlocked phone; can be used with any carrier and SIM card
Pre-loaded software tools include; Stopwatch, Calendar, Alarm, World Clock, Calculator, Currency Converter, Melody Composer, Video Games
Full bluetooth support; contains profiles for NINE bluetooth mobile phone services
Powerful built-in MIC and speaker; hear your phone ringtones and sound effects clearly
GSM Compatibility: Dual Band 900MHz, 1800MHz
GPRS Support: YES
Screen: 1.3 inch OLED, 128×160 with 260K colors
Memory: 1GB internal TF/microSD card
SIM Card Slot: YES - 1
Bluetooth Profiles: Handsfree, Headset, A2DP, AVRCP, SPP, DUN, OPP, FTP, BPP, HID - All Supported
Mobile Internet: WAP, Email - (if supported by your network provider)
Messages: SMS, MMS, EMS, Voice Mail Server, Broadcast Message (from provider)
1.3 Megapixel Still Camera, Resolution: 640×480, 320×240, 160×120, 128×128
Video Camera, Resolution: 128×128 - MPEG4 or H.263
Video Formats: MPEG, 3GP - Picture Formats: JPEG, BMP, GIF - Music and Sound Formats: MP3, MIDI, WAV, AMR, AWB
Battery Life: Talk Time: Up to 1.5 hrs, Music Play: Up to 4 hrs, Stand By: Up to 150 hrs
System: Windows 98SE / ME / 2000 / XP / Vista, MAC OS 9.2.2 or above
Languages: English, Spanish, Danish, Portuguese, Italian, German, Arabic, Chinese
Dimension: Face - 60mm x 19mm; Strap Max Length - 240mm
The 1GB Clamshell Cell Phone Watch with Bluetooth is available from the Chinavision website for 104.97 Euros (about $142 USD).
10.13.2008
10.09.2008
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